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Stem cell therapy in inflammatory bowel disease: A promising therapeutic strategy?. [revisión]

Por: Flores de la Cal, Ana Isabel [Banco de Sangre de Cordón Umbilical] | Gómez Gómez, Gonzalo Jesús [Aparato Digestivo] | Masedo González, Ángeles [Aparato Digestivo] | Martínez Montiel, Pilar [Aparato Digestivo].
Colaborador(es): Servicio de Medicina del Aparato Digestivo | Instituto de Investigación imas12.
Tipo de material: materialTypeLabelArtículoEditor: World journal of stem cells, 2015Descripción: 7(2):343-51.Recursos en línea: Acceso libre Resumen: Inflammatory bowel diseases are inflammatory, chronic and progressive diseases of the intestinal tract for which no curative treatment is available. Research in other fields with stem cells of different sources and with immunoregulatory cells (regulatory T-lymphocytes and dendritic T-cells) opens up new expectations for their use in these diseases. The goal for stem cell-based therapy is to provide a permanent cure. To achieve this, it will be necessary to obtain a cellular product, original or genetically modified, that has a high migration capacity and homes into the intestine, has high survival after transplantation, regulates the immune reaction while not being visible to the patient's immune system, and repairs the injured tissue.
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Tipo de ítem Ubicación actual Signatura Estado Fecha de vencimiento
Revisión Revisión PC17384 (Navegar estantería) Disponible

Formato Vancouver:
Flores AI, Gómez Gómez GJ, Masedo González Á, Martínez Montiel MP. Stem cell therapy in inflammatory bowel disease: A promising therapeutic strategy?. World J Stem Cells. 2015 Mar 26;7(2):343-51.

PMID: 25815119
PMC4369491

Contiene 84 referencias

Inflammatory bowel diseases are inflammatory, chronic and progressive diseases of the intestinal tract for which no curative treatment is available. Research in other fields with stem cells of different sources and with immunoregulatory cells (regulatory T-lymphocytes and dendritic T-cells) opens up new expectations for their use in these diseases. The goal for stem cell-based therapy is to provide a permanent cure. To achieve this, it will be necessary to obtain a cellular product, original or genetically modified, that has a high migration capacity and homes into the intestine, has high survival after transplantation, regulates the immune reaction while not being visible to the patient's immune system, and repairs the injured tissue.

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